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av A Andersson · 2012 — The gene and protein are very similar to the closely related c-Myc protein, except for the 3´untranslated region (3´UTR), suggesting that it may

To obtain a complete collection of full-length 3'UTR sequences of mRNAs of Eph receptors and ephrin ligands, we first extracted all available mouse Eph/ephrin sequences from the GenBank database of the NCBI. The 3′UTR features a variable region, followed by a poly(U/UC) tract and a 3′X region with three predicted stem loops (3′SL1-3) ( Figure 1 B). Along with the HCV 5′UTR, which includes an internal ribosome entry site (IRES) ( Figure 1 A), the highly conserved 98-nt 3′X region is critical for viral replication ( 11 ). 上流の非翻訳領域は5' 非翻訳領域（5' UTR：Five prime untranslated region）と呼ばれ、その5' 端は成熟mRNA ではキャップ構造の付加が起こる。一方下流の非翻訳領域は 3' 非翻訳領域（3' UTR：Three prime untranslated region）と呼ばれ、その3' 端は成熟mRNA ではポリアデニル化によりpoly(A) 鎖の付加が起こる。 3' UTR In genetics, the 3' UTR (read as 3 prime untranslated region) is a particular section of messenger RNA ().. Like all strands of nucleic acid, mRNA is directional. One end is the 5' (five prime) end: the other is the 3' (three prime) end. UTR is a rating system that provides a single, unifying language and standard for tennis players across ages, geography, gender and economics.

The cap and the poly (A)tail mentioned in the image are added to the mRNA to prevent the mRNA from being degraded by enzymes in the cell. If it is found on the 5' side, it is called the 5' UTR (or leader sequence), or if it is found on the 3' side, it is called the 3' UTR (or trailer sequence). mRNA is RNA that carries information from DNA to the ribosome, the site of protein synthesis (translation) within a cell. The 3’-UTR plasmids provide a convenient solution for quantitative assessment of the inhibitory effect between miRNAs and their potential target genes. The 3’-UTR sequence of a gene of interest was cloned downstream of the firefly luciferase gene. The untranslated regions (UTRs) at the 3'end of mRNA transcripts contain important sequences that influence the fate of mRNA and thus proteosynthesis.

sv – Svenska. Version 09/07/2015 16:42:00. 1/3. SKATTEREGISTRERINGSNUMMER (TIN) Det nyaste TIN-liknande numret är det unika skattenumret (UTR).

Exempelvis har samband mellan polymorfismer i HLA-G 3'UTR-regionen och utveckling av kolorektal cancer upptäckts. of cDNA ends(RACE).

upstream open reading frame; UTR; untranslated region. Introduction. A growing body of evidence has

However, it is now known that the untranslated region of mRNA is involved in many regulatory aspects of gene expression in eukaryotic organisms. Relative to the 5′ UTR, the DENV 3’UTR is longer (around 450 nucleotides) and lacks a poly (A) tail, but contains a number of conserved RNA structures that are essential for viral replication.

Housekeeping gene 3´UTR vectors: Housekeeping control constructs contain the 3´UTRs for common housekeeping genes cloned downstream of the RenSP luciferase reporter gene. Random control 3´UTR vectors: Random control constructs contain non-conserved, non-genic, and non-repetitive human genomic fragments. Here, we report The Cancer 3' UTR Atlas (TC3A), a comprehensive resource of APA usage for 10,537 tumors across 32 cancer types.
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Zoals alle strengen nucleïnezuur heeft mRNA een bepaalde richting. Het ene eind is het 5' eind (five prime end) en het andere einde het 3'eind (three prime end). Het ribosoom begint bij het vormen van een eiwit met het aflezen ( translatie) van het mRNA aan het 5' eind La 3' UTR (chiamata anche sequenza trailer) è la regione dell' mRNA collocata a valle della CDS (sequenza codificante di un gene) e segue immediatamente il codone di terminazione di traduzione di un gene. La 3' UTR influenza la poliadenilazione, l'efficienza di traduzione ,la localizzazione e la stabilità dell' mRNA. Se hela listan på de.wikipedia.org Las regiones 3´ UTR gobiernan la expresión de los genes gracias a la interacción entre los componentes estructurales del RNAm (elementos en cis) y factores específicos que actúan en trans (proteínas que se unen a RNA y RNAs no codificantes).

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3′-untranslated regions (3′-UTRs) are the noncoding parts of mRNAs. Compared to yeast, in humans, median 3′-UTR length has expanded approximately

3'UTR异构体比率因细胞类型而异，并随信号通路的激活而变化 The 3' UTR of guinea pig is 771 nt long and shows higher similarity with human than with rodent sequences, having a region of about 350 nt that is deleted in rat and mouse.